Author

Y. T. Zhao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

D. Baker· 2 shared G. Ueda· 2 shared H. Ruohola-Baker· 2 shared J. A. Fallas· 2 shared J. Mathieu· 2 shared S. Saini· 2 shared A. C. Walls· 1 shared A. Etemadi· 1 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

D. Baker

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Designed proteins assemble antibodies into modular nanocages

R. Divine, H. V. Dang, G. Ueda, J. A. Fallas, I. Vulovic, W. Sheffler, S. Saini, Y. T. Zhao, I. X. Raj, P. A. Morawski, M. F. Jennewein, L. J. Homad, Y.-H. Wan, M. R. Tooley, F. Seeger, , D. Baker

The paper designs modular nanocages that assemble antibodies into precise geometries, enhancing signaling and neutralization compared to free antibodies.

bioRxiv · Dec 1, 2020Biochemistry

F-domain valency determines outcome of signaling through the angiopoietin pathway

Y. T. Zhao, J. A. Fallas, S. Saini, G. Ueda, L. Somasundaram, Z. Zhou, I. Xavier, D. Ehnes, C. Xu, L. Carter, S. Wrenn, J. Mathieu, D. L. Sellers, D. Baker, H. Ruohola-Baker

The paper investigates how the valency of F-domain scaffolds affects signaling through the angiopoietin pathway, finding that higher valency mimics Ang1's pro-angiogenic effects while lower valency mimics Ang2's antagonistic effects.

bioRxiv · Sep 19, 2020Biochemistry

Targeting Aryl Hydrocarbon Receptor with small molecule, 1'H-indole-3'-carbonyl -thiazole-4-carboxylic acid methyl ester blocked human glioma cell invasion via MYH9

l. j. Zhao, Q. t. Shu, H. Sun, Y. l. Ma, D. d. Kang, Y. t. Zhao, J. Lu, P. Gong, F. Yang, f. Wan

The paper shows that ITE, an AHR ligand, inhibits glioma cell migration and invasion by reducing MYH9 expression, which is critical for cell motility.

bioRxiv · Jan 13, 2020Cell Biology