L. K. Engelbrecht

A strategy to address dissociation-induced compositional and transcriptional bias for single-cell analysis of the human mammary gland

The paper presents a strategy to minimize dissociation-induced biases in single-cell analysis of human mammary glands by comparing different dissociation methods using single-cell RNA sequencing and flow cytometry.

Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk

This study uses single-cell RNA sequencing to analyze mammary epithelial cells from human milk and non-lactating breast tissue, identifying distinct luminal cell clusters and their functional differences during lactation.