H. M. Ganz

A strategy to address dissociation-induced compositional and transcriptional bias for single-cell analysis of the human mammary gland

The paper presents a strategy to minimize dissociation-induced biases in single-cell analysis of human mammary glands by comparing different dissociation methods using single-cell RNA sequencing and flow cytometry.

Cell density-dependent ferroptosis in breast cancer is induced by accumulation of polyunsaturated fatty acid-enriched triacylglycerides

This study shows that low cell density in breast cancer cells increases ferroptosis sensitivity by promoting PUFA-enriched TAG accumulation and reducing lipid desaturation.