M. Sterr

Chronic intermittent fasting impairs β-cell maturation and function in adolescent mice

This study shows chronic intermittent fasting impairs β-cell maturation and function in adolescent mice, but not in adults, with similar patterns observed in human type 1 diabetes.

Space-time dynamics of genome replication studied with super-resolved microscopy

The paper uses super-resolved microscopy to study genome replication dynamics in mouse myeloblast cells, revealing shifts in DNA compaction and labeling patterns during replication.

True-to-scale DNA-density maps correlate with major accessibility differences between active and inactive chromatin

The paper presents true-to-scale DNA-density maps of human and mouse nuclei, revealing significant accessibility differences between active and inactive compartments.

Multi-omics and 3D-imaging reveal bone heterogeneity and unique calvaria cells in neuroinflammation

The paper uses multi-omics and 3D-imaging to show that calvaria bone marrow has a distinct molecular profile and contributes to neuroinflammation.

A strategy to address dissociation-induced compositional and transcriptional bias for single-cell analysis of the human mammary gland

The paper presents a strategy to minimize dissociation-induced biases in single-cell analysis of human mammary glands by comparing different dissociation methods using single-cell RNA sequencing and flow cytometry.