Author

L. Kergoat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:bacteria (other)· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

H. Bourhy· 3 shared F. Larrous· 2 shared A. Addetia· 1 shared A. C. Walls· 1 shared A. Ceschi· 1 shared A. De Marco· 1 shared A. Komarova· 1 shared A. Lanzavecchia· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersImmunology

H. Bourhy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

High-throughput Tn-seq screens identify both known and novel Pseudomonas putida KT2440 genes involved in metal resistance

K. Royet, L. Kergoat, S. Lutz, C. Oriol, N. Parisot, C. Schori, C. H. Ahrens, A. Rodrigue, E. Gueguen

This study uses Tn-seq to identify metal resistance genes in Pseudomonas putida, revealing both known and novel genes involved in cadmium, copper, and cobalt resistance.

bioRxiv · Apr 12, 2024Microbiology

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

Y.-J. Park, D. Pinto, A. C. Walls, Z. Liu, A. De Marco, F. Benigni, F. Zatta, C. Silacci-Fregni, J. Bassi, K. R. Sprouse, A. Addetia, J. E. Bowen, C. Stewart, M. Giurdanella, C. Saliba, , Piccoli

This study shows that hybrid immunity and vaccine boosters provide potent neutralizing activity against Omicron BA.1 and BA.2, while breakthrough infections induce nasal mucosal neutralization and identify an ultrapotent pan-variant antibody.

bioRxiv · May 8, 2022Immunology

Recognition of copy-back defective interfering rabies virus genomes by RIG-I triggers the antiviral response against vaccine strains

w. AOUADI, V. Najburg, R. Legendre, H. Varet, L. Kergoat, F. Tangy, F. Larrous, A. Komarova, H. Bourhy

This study shows that pathogenic RABV strains lack defective interfering genomes, leading to weak antiviral responses, while attenuated vaccine strains release 5cb DI genomes that enhance RIG-I-mediated IFN signaling and antiviral activity.

bioRxiv · Mar 24, 2022 · PreprintMicrobiology

Anti-COVID-19 efficacy of ivermectin in the golden hamster

G. D. de Melo, F. Lazarini, F. Larrous, L. Feige, L. Kergoat, A. Marchio, P. Pineau, M. Lecuit, P.-M. Lledo, J.-P. Changeux, H. Bourhy

This study evaluates ivermectin's efficacy against SARS-CoV-2 in golden hamsters, finding it reduces inflammation and neurological symptoms without affecting viral load.

bioRxiv · Nov 21, 2020Immunology