Author

L. Klechka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:metabolomics· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. A. Dean· 2 shared E. Hossain· 2 shared L.-I. McCall· 2 shared A. R. Parab· 1 shared C. Pan· 1 shared J. Roach· 1 shared K. Eaton· 1 shared K. Wheeler· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersMicrobiology

D. A. Dean

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Persistent biofluid small molecule alterations induced by Trypanosoma cruzi infection are not restored by antiparasitic treatment

D. A. Dean, J. Roach, R. Ulrich vonBargen, Y. Xiong, S. S. Kane, L. Klechka, K. Wheeler, M. Jimenez Sandoval, M. Lesani, E. Hossain, M. Katemauswa, M. Schaefer, M. Harris, S. Barron, Z. Liu, , L.-I. McCall

This study identifies persistent urine metabolome alterations in T. cruzi-infected mice that are not reversed by antiparasitic treatment, suggesting urine as a potential diagnostic tool for Chagas Disease.

bioRxiv · Jun 3, 2023Microbiology

Spatial metabolomics reveals localized impact of influenza virus infection on the lung tissue metabolome

D. A. Dean, L. Klechka, E. Hossain, A. R. Parab, K. Eaton, M. Hinsdale, L.-I. McCall

This study uses spatial metabolomics to analyze metabolic changes in lung tissue and plasma of influenza-infected mice, identifying site-specific metabolite alterations and their potential as therapeutic targets.

bioRxiv · Nov 22, 2021Microbiology