ImmunologybioRxiv
Inhibitory CD200-receptor signaling is rewired by type I interferon
M. van der Vlist, M. I. Pascoal Ramos, L. L. van den Hoogen…·L. Meyaard
This study shows that type I interferon alters CD200R signaling by promoting RasGAP cleavage, converting CD200R from an inhibitor to a potentiator of IFNG mRNA production in SLE patients.
DOI 10.1126/scisignal.abb4324