Author

M. van der Kroef

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

S. Hiddingh· 2 shared A. C. Hinrichs· 1 shared A. J. Affandi· 1 shared A. Ottria· 1 shared A. Pandit· 1 shared C. G. K. Wichers· 1 shared C. P. J. Bekker· 1 shared E. Chouri· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

S. Hiddingh

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Nuclear receptor subfamily 4A signaling as a key disease pathway of CD1c+ dendritic cell dysregulation in systemic sclerosis

N. H. Servaas, S. Hiddingh, E. Chouri, C. G. K. Wichers, A. J. Affandi, A. Ottria, C. P. J. Bekker, M. Cossu, S. Silva-Cardoso, M. van der Kroef, A. C. Hinrichs, T. Carvalheiro, N. Vazirpanah, L. Beretta, M. Rossato, , A. Pandit

This study identifies NR4A nuclear receptor subfamily genes as key regulators of immune and fibrosis pathways in SSc cDC2s through transcriptomic and network analysis, with functional validation using ChIP-sequencing and in vitro experiments.

bioRxiv · Nov 8, 2021Immunology

Inhibitory CD200-receptor signaling is rewired by type I interferon

M. van der Vlist, M. I. Pascoal Ramos, L. L. van den Hoogen, S. Hiddingh, L. Timmerman, T. A. P. de Hond, E. D. Kaan, M. van der Kroef, R. J. Lebbink, F. M. A. Peters, W. Khoury-Hanold, R. Fritsch-Stork, T. Radstake, L. Meyaard

This study shows that type I interferon alters CD200R signaling by promoting RasGAP cleavage, converting CD200R from an inhibitor to a potentiator of IFNG mRNA production in SLE patients.

bioRxiv · Feb 6, 2020Immunology