Author

L. Lewis-Tuffin

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

J. N. Sarkaria· 1 shared L. M. Cooper· 1 shared P. Z. Anastasiadis· 1 shared R. W. Feathers· 1 shared W.-H. Lin· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCancer Biology

J. N. Sarkaria

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1 paper

Recent·Most cited

A Syx-RhoA-Dia1 signaling axis regulates cell cycle progression, DNA damage, and therapy resistance in glioblastoma

W.-H. Lin, R. W. Feathers, L. M. Cooper, L. Lewis-Tuffin, J. N. Sarkaria, P. Z. Anastasiadis

This study identifies a Syx-RhoA-Dia1-YAP/TAZ signaling axis that promotes glioblastoma growth, DNA damage, and therapy resistance, suggesting it as a therapeutic target.

bioRxiv · Dec 3, 2021Cancer Biology