P. Z. Anastasiadis

This study uses cell-specific proteomics to show that CTSB signaling from glioblastoma cells promotes malignancy by disrupting neurogenesis and inducing senescence in neural progenitor cells near the subventricular zone.

This study identifies a Syx-RhoA-Dia1-YAP/TAZ signaling axis that promotes glioblastoma growth, DNA damage, and therapy resistance, suggesting it as a therapeutic target.

This study characterizes human Syx, a RhoGEF involved in glioblastoma, and performs computational simulations to elucidate its structure and allosteric regulation.