Author

L. M. Leong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:fluorescence / live-cell microscopy· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

B. J. Baker· 2 shared B. E. Kang· 1 shared G. Mueller· 1 shared H. M. Miettinen· 1 shared J. A. Davisson· 1 shared J. J. Kelley· 1 shared K. Miyazaki· 1 shared M. Fisher· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

B. J. Baker

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2 papers

Recent·Most cited

S1 hydrophobic residues modulate voltage sensing phosphatase enzymatic function and voltage sensing

V. Rayaprolu, H. M. Miettinen, W. Baker, V. C. Young, M. Fisher, G. Mueller, W. O. Rankin, J. J. Kelley, W. Ratzan, L. M. Leong, J. A. Davisson, B. J. Baker, S. C. Kohout

This study shows that S1 hydrophobic residues in voltage sensing phosphatase (VSP) modulate voltage sensing and enzymatic activity by altering voltage dependence and kinetics.

bioRxiv · Dec 27, 2023Biophysics

Proton wires mediate the optical signal for ArcLight-type Genetically Encoded Voltage Indicators

B. E. Kang, L. M. Leong, Y. Kim, K. Miyazaki, W. Ross, B. J. Baker

This paper investigates how proton wires in ArcLight-type GEVIs mediate voltage-dependent optical signals through electrostatic interactions and shows that excitation wavelength affects the polarity and kinetics of the response.

bioRxiv · Oct 6, 2020 · PreprintBiophysics