Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice
L. M. Podmore, Y. Poloz, C. Iorio, S. Mouaaz, K. Nixon, P. Smirnov, B. McDonnell, S. Lam, B. Zhang, P. Tharmapalan, S. Sarkar, F. Vyas, M. Ennis, R. Dowling, V. Stambolic
This study shows that insulin receptor loss delays mammary tumor onset and burden in mouse models, without affecting progression or metastasis.
bioRxiv · May 6, 2022Cancer Biology