S. Mouaaz

NEK10 tyrosine phosphorylates β-catenin to regulate its cytoplasmic turnover.

This study identifies Nek10 as a tyrosine kinase that phosphorylates β-catenin to regulate its cytoplasmic turnover and tumor-forming capacity.

Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice

This study shows that insulin receptor loss delays mammary tumor onset and burden in mouse models, without affecting progression or metastasis.