Author

V. Stambolic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

N. Haider· 3 shared B. van de Kooij· 2 shared M. B. Yaffe· 2 shared P. Dutt· 2 shared S. Mouaaz· 2 shared A. E. Casey· 1 shared A. Golaraei· 1 shared A. Schimmer· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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3 shared papersCancer Biology

N. Haider

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

NEK10 tyrosine phosphorylates β-catenin to regulate its cytoplasmic turnover.

P. Dutt, N. Haider, S. Mouaaz, L. Podmore, V. Stambolic

This study identifies Nek10 as a tyrosine kinase that phosphorylates β-catenin to regulate its cytoplasmic turnover and tumor-forming capacity.

bioRxiv · Dec 23, 2022 · PreprintCancer Biology

Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice

L. M. Podmore, Y. Poloz, C. Iorio, S. Mouaaz, K. Nixon, P. Smirnov, B. McDonnell, S. Lam, B. Zhang, P. Tharmapalan, S. Sarkar, F. Vyas, M. Ennis, R. Dowling, V. Stambolic

This study shows that insulin receptor loss delays mammary tumor onset and burden in mouse models, without affecting progression or metastasis.

bioRxiv · May 6, 2022Cancer Biology

Wide-Field Multicontrast Nonlinear Microscopy for Histopathology

L. Uribe Casta\~no, K. Mirsanaye, A. Golaraei, L. Kontenis, S. J. Done, V. Stambolic, M. Akens, B. Wilson, V. Barzda

The paper develops a multicontrast microscope for histopathology imaging, optimizing conditions for H&E stained slides and analyzing collagen organization.

bioRxiv · Apr 16, 2022 · PreprintBiophysics

Mammary epithelial cells have lineage-restricted metabolic identities

M. Mahendralingam, K. Aliar, A. E. Casey, D. Pellacani, H. Kim, V. Ignatchenko, M. G. Valero, L. Palomero, A. Sinha, V. Stambolic, M. Alam, A. Schimmer, H. Berman, M. A. Pujana, C. J. Eaves, , R. Khokha

The paper identifies lineage-restricted metabolic identities in normal mammary epithelial cells and links them to breast cancer metabolic heterogeneity.

bioRxiv · Oct 8, 2019Cell Biology

NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity

N. Haider, P. Dutt, B. van de Kooij, M. B. Yaffe, V. Stambolic

This study identifies NEK10 as a kinase that phosphorylates p53 on Y327, modulating its transcriptional activity and affecting cellular proliferation and response to DNA damage.

bioRxiv · Jan 10, 2019Cancer Biology

Comprehensive substrate specificity profiling of the human nek kinome reveals unexpected signaling outputs

B. van de Kooij, P. Creixell, A. van Vlimmeren, B. Joughin, C. J. Miller, N. Haider, R. Linding, V. Stambolic, B. E. Turk, M. B. Yaffe

The paper identifies phosphorylation-site motifs for the human Nek kinome, revealing dual-specificity in Nek10 and motif similarity between Nek6/7/9 and Plk1.

bioRxiv · Jan 8, 2019Biochemistry