Author

F. Vyas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

K. Aliar· 4 shared R. Khokha· 4 shared B. Zhang· 3 shared B. T. Grünwald· 2 shared C. W. McCloskey· 2 shared N. Chan· 2 shared N. Krebs· 2 shared P. Bronsert· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

K. Aliar

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

FABP7 Progenitors are a Targetable Metabolic Root in the BRCA1 Breast

C. W. McCloskey, B. Zhang, M. Waas, G. Abazari, F. Vyas, K. Aliar, P. Tharmapalan, A. Kuttanamkuzhi, S. Narala, J. Cruikshank, S. O. P. Hofer, H. W. Jackson, T. Kislinger, H. K. Berman, R. Khokha

This study identifies FABP7 progenitors as a targetable metabolic root in BRCA1 breast cancer, showing their dysregulation and potential inhibition via fatty acid metabolism disruption.

bioRxiv · Nov 2, 2023 · PreprintCell Biology

Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response via AP1 dichotomy in pancreatic cancer

L. Klein, M. Tu, N. Krebs, L. Urbach, D. G. Grimm, M. U. Latif, F. Penz, N. Chan, K. Aliar, F. Vyas, U. Kishore, E. Hessmann, A. Trumpp, E. Espinet, A. Papantonis, , S. K. Singh

The paper identifies AP1 transcription factor dichotomy and CD68+ macrophages as drivers of intratumoral subtype co-existence and therapy response in pancreatic cancer.

bioRxiv · Oct 30, 2023 · PreprintCancer Biology

Hourglass, a tool to mine bioimaging data, uncovers sex-disparities in the IL-6-associated T cell response in pancreatic tumors

K. Aliar, H. R. Waterhouse, F. Vyas, N. Krebs, E. Poulton, B. Zhang, N. Chan, P. Bronsert, S. E. Fischer, S. Gallinger, B. T. Grünwald, R. Khokha

Hourglass processes bioimaging data to reveal sex-specific IL-6 effects on T cell responses in pancreatic tumors.

bioRxiv · Sep 12, 2022 · PreprintCancer Biology

Insulin Receptor Loss Impairs Mammary Tumorigenesis in Mice

L. M. Podmore, Y. Poloz, C. Iorio, S. Mouaaz, K. Nixon, P. Smirnov, B. McDonnell, S. Lam, B. Zhang, P. Tharmapalan, S. Sarkar, F. Vyas, M. Ennis, R. Dowling, V. Stambolic

This study shows that insulin receptor loss delays mammary tumor onset and burden in mouse models, without affecting progression or metastasis.

bioRxiv · May 6, 2022Cancer Biology

Spatially confined sub-tumor microenvironments orchestrate pancreatic cancer pathobiology

B. T. Grünwald, A. Devisme, G. Andrieux, F. Vyas, K. Aliar, C. W. McCloskey, A. Macklin, G. H. Jang, R. Denroche, J. M. Romero, P. Bavi, P. Bronsert, F. Notta, G. O'Kane, J. Wilson, , R. Khokha

This study identifies spatially confined sub-tumor microenvironments in PDAC that drive distinct tumor progression outcomes.

bioRxiv · Feb 18, 2021Cancer Biology