Interleukin-33 regulates metabolic reprogramming of the retinal pigment epithelium in response to immune stressors.
L. M. Scott, E. E. Vincent, N. Hudson, C. Neal, N. Jones, E. Lavelle, M. Campbell, A. Halestrap, A. D. Dick, S. Theodoropoulou
This study identifies IL-33 as a metabolic checkpoint in RPE cells that regulates mitochondrial respiration and metabolic adaptation to immune stressors.
bioRxiv · Feb 4, 2021Immunology