Author

L. Matthews

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cell Biology· 1 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Anyamba· 1 shared A. Freeman· 1 shared A. Kemp· 1 shared A. Muppirala· 1 shared A. Robinson· 1 shared A. Shepherd· 1 shared C. Cordel· 1 shared C. Ferrari· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperEcology

A. Anyamba

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Localized Rift Valley Fever Virus Persistence Depends on a High Transovarial Transmission Fraction

M. K. Rostal, J. Prentice, N. Ross, A. Kemp, P. Thompson, A. Anyamba, S. Cleaveland, C. Cordel, V. Msimang, P. Jansen van Vuren, D. Haydon, W. B. Karesh, J. Paweska, L. Matthews

This study models Rift Valley fever virus persistence via transovarial transmission and finds that a high TOT fraction enables localized persistence with realistic seroprevalence patterns.

bioRxiv · Oct 27, 2023 · PreprintEcology

Sterically enhanced control of enzyme-assisted DNA assembly

O. J. Irving, L. Matthews, S. Coulthard, R. K. Neely, M. M. Grant, T. Albrecht

This paper introduces a method to overcome size limitations in DNA assembly by using steric control to enhance enzymatic activity, enabling the creation of functionalised DNA structures with multiple probes.

bioRxiv · Feb 27, 2023Biochemistry

RET Signaling Persists in the Adult Intestine and Stimulates Motility by Limiting PYY Release from Enteroendocrine Cells

A. Shepherd, L. Feinstein, S. Sabel, D. Rastelli, E. Mezhibovsky, L. Matthews, A. Muppirala, A. Robinson, M. D. Gershon, M. Rao

This study shows RET signaling in the adult intestine limits PYY release from L-cells, which is necessary for normal gut motility in male mice.

bioRxiv · Apr 15, 2022Cell Biology

An inactivated multivalent influenza A virus vaccine is broadly protective in mice and ferrets

J. Park, S. Fong, L. M. Schwartzman, Z.-M. Sheng, A. Freeman, L. Matthews, Y. Xiao, M. D. Ramuta, N. A. Batchenkova, L. Qi, L. A. Rosas, S. Williams, K. Scherler, M. Gouzoulis, I. Bellayr, , J. K. Taubenberger

This study shows an inactivated multivalent influenza A vaccine provides broad protection against diverse IAV subtypes in mice and ferrets, including non-vaccine strains, suggesting its potential as a universal vaccine.

bioRxiv · Sep 10, 2021Microbiology

One Health or Three? Transmission modelling of Klebsiella isolates reveals ecological barriers to transmission between humans, animals and the environment

H. A. Thorpe, R. Booton, T. Kallonen, M. J. Gibbon, N. Couto, V. A. Passet, J. Fernandez, C. Rodrigues, L. Matthews, S. Mitchell, R. Reeve, S. David, C. Merla, M. Corbella, C. Ferrari, , E. J. Feil

This study models Klebsiella transmission across human, animal, and environmental sources, finding limited AMR spread outside clinical settings and human-to-human transmission dominance.

bioRxiv · Aug 5, 2021 · PreprintMicrobiology