Author

H. A. Thorpe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

J. Corander· 4 shared C. Merla· 2 shared C. Rodrigues· 2 shared D. Sassera· 2 shared E. J. Feil· 2 shared M. Corbella· 2 shared O. Samuelsen· 2 shared P. J. Johnsen· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersMicrobiology

J. Corander

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Plasmid-driven strategies for clone success in Escherichia coli

S. Arredondo-Alonso, A. K. Pontinen, J. Gama, R. A. Gladstone, K. Harms, G. Tonkin-Hill, H. A. Thorpe, G. S. Simonsen, O. Samuelsen, P. J. Johnsen, J. Corander

The paper uses long-read sequencing to analyze plasmids and chromosomes in E. coli over two decades, revealing long-term plasmid-lineage associations and success strategies.

bioRxiv · Oct 14, 2023 · PreprintMicrobiology

Strong pathogen competition in neonatal gut colonisation

T. Mäklin, H. A. Thorpe, A. K. Pöntinen, R. A. Gladstone, Y. Shao, M. Pesonen, A. McNally, P. J. Johnsen, O. Samuelsen, T. D. Lawley, A. Honkela, J. Corander

This study quantifies strain-level colonisation dynamics of gut pathogens in neonates, finding strong competition and some synergies, and reveals pathogenic potential differences among ExPEC clones.

bioRxiv · Jun 19, 2022Microbiology

One Health or Three? Transmission modelling of Klebsiella isolates reveals ecological barriers to transmission between humans, animals and the environment

H. A. Thorpe, R. Booton, T. Kallonen, M. J. Gibbon, N. Couto, V. A. Passet, J. Fernandez, C. Rodrigues, L. Matthews, S. Mitchell, R. Reeve, S. David, C. Merla, M. Corbella, C. Ferrari, , E. J. Feil

This study models Klebsiella transmission across human, animal, and environmental sources, finding limited AMR spread outside clinical settings and human-to-human transmission dominance.

bioRxiv · Aug 5, 2021 · PreprintMicrobiology

Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations

H. A. Thorpe, E. Tourrette, K. Yahara, F. F. Vale, S. Liu, M. Oleastro, T. Alarcon, T. Perets, S. Latifi-Navid, Y. Yamaoka, B. Martinez-Gonzalez, I. Karayiannis, T. Karamitros, D. Sgouras, W. Elamin, , D. Falush

This study shows H. pylori has spread repeatedly from Africa by replacing strains with deleterious mutations through migration and selection.

bioRxiv · Jun 5, 2021Evolutionary Biology

Description of Klebsiella spallanzanii sp. nov. and of Klebsiella pasteurii sp. nov.

C. Merla, C. Rodrigues, V. Passet, M. Corbella, H. A. Thorpe, T. V. S. Kallonen, Z. Zong, P. Marone, C. Bandi, D. Sassera, J. Corander, E. J. Feil, S. Brisse

This paper describes two new Klebsiella species, K. spallanzanii and K. pasteurii, based on genomic and biochemical analyses of phylogroups Ko3 and Ko4, with type strains isolated from various sources.

bioRxiv · Jul 16, 2019Microbiology