Single-molecule analysis reveals TDG exhibits multiple modes of linear diffusion to process 5-formylcytosine.
B. L. Schnable, M. A. Schaich, V. Roginskaya, L. P. Leary, T. M. Weaver, B. D. Freudenthal, A. C. Drohat, B. Van Houten
This study uses single-molecule fluorescence to show TDG uses multiple diffusion modes to search for DNA lesions and how its structure affects nucleosome interactions.
bioRxiv · Oct 4, 2023Biophysics