Author

L. P. Marcelino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

K. H. Gardner· 2 shared X. Xu· 2 shared B. A. Johnson· 1 shared D. C. Favaro· 1 shared D. Gagne· 1 shared E. A. Isiorho· 1 shared J. Closson· 1 shared J. M. Aramini· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

K. H. Gardner

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2 papers

Recent·Most cited

Identification of Small Molecule Ligand Binding Sites On and In the ARNT PAS-B Domain

X. Xu, J. Closson, L. P. Marcelino, D. C. Favaro, M. L. Silvestrini, R. Solazzo, L. T. Chong, K. H. Gardner

The paper identifies ligand-binding sites on and within the ARNT PAS-B domain using NMR, MD simulations, and ensemble docking, revealing distinct binding modes for three small molecules.

bioRxiv · Nov 3, 2023Biochemistry

Use of High Pressure NMR Spectroscopy to Rapidly Identify Proteins with Internal Ligand-Binding Voids

D. Gagne, R. Azad, J. M. Aramini, X. Xu, E. A. Isiorho, U. R. Edupuganti, J. P. Williams, L. P. Marcelino, B. A. Johnson, K. Akasaka, K. H. Gardner

This paper introduces a method using high-pressure NMR spectroscopy to identify proteins with internal ligand-binding voids by detecting nonlinear chemical shift changes in 1H/15N HSQC experiments.

bioRxiv · Aug 25, 2020 · PreprintBiophysics