A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity
P. Dedhia, H. Sivakumar, M. A. Rodriguez, K. G. Nairon, J. M. Zent, X. Zheng, K. Jones, L. Popova, J. L. Leight, A. Skardal
This paper develops a 3D adrenocortical carcinoma tumor platform to study drug response and MMP activity, showing decreased drug sensitivity and active MMP-mediated invasion in 3D.
bioRxiv · Jan 24, 2023Cancer Biology