Author

L. R. Bonser

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

D. J. Erle· 3 shared K. D. Koh· 3 shared L. T. Zlock· 3 shared W. E. Finkbeiner· 3 shared W. L. Eckalbar· 3 shared D. I. Sun· 2 shared J. Shen· 2 shared D. Cheng· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersCell Biology

D. J. Erle

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Author profile →

3 papers

Recent·Most cited

Targeting a central feature of asthma using a cell type-selective IL-13-responsive enhancer

K. D. Koh, L. R. Bonser, W. L. Eckalbar, J. Shen, O. Yizhar-Barnea, X. Zeng, D. I. Sun, L. T. Zlock, W. E. Finkbeiner, N. Ahituv, D. J. Erle

The paper identifies cell type-selective IL-13-responsive enhancers in airway epithelial cells and demonstrates their therapeutic potential for asthma by targeting mucin production.

bioRxiv · Oct 8, 2021 · PreprintImmunology

The type 2 asthma mediator IL-13 inhibits SARS-CoV-2 infection of bronchial epithelium

L. R. Bonser, W. L. Eckalbar, L. Rodriguez, J. Shen, K. D. Koh, L. T. Zlock, S. Christenson, P. G. Woodruff, W. E. Finkbeiner, D. J. Erle

This study shows IL-13 reduces SARS-CoV-2 infection in bronchial epithelial cells by altering gene expression and inhibiting viral replication.

bioRxiv · Feb 25, 2021Cell Biology

Flow cytometric analysis and purification of airway epithelial cell subsets

L. R. Bonser, K. D. Koh, K. Johansson, S. P. Choksi, D. Cheng, L. Liu, D. I. Sun, L. T. Zlock, W. L. Eckalbar, W. E. Finkbeiner, D. J. Erle

The paper develops flow cytometric panels to isolate human airway epithelial subsets using scRNA-seq data and cell type markers, identifying subpopulations and low-abundance transcripts in secretory cells.

bioRxiv · Apr 20, 2020Cell Biology