Author

L. R. Lopes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

P. Syrris· 2 shared B. L. Parker· 1 shared D. A. Elliott· 1 shared D. D. Chung· 1 shared D. Puehringe· 1 shared E. M. Perry· 1 shared E. R. Porrello· 1 shared F. Bolk· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

P. Syrris

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Unlocking Predictive Power: A Machine Learning Tool Derived from In-Depth Analysis to Forecast the Impact of Missense Variants in Human Filamin C

M. Nagy, G. Mlynek, J. Kostan, L. Smith, D. Puehringe, P. Charron, T. B. Rasmussen, Z. Bilinska, M. M. Akhtar, P. Syrris, L. R. Lopes, P. M. Elliott, M. Gautel, O. Carugo, K. Djinovic-Carugo

The paper develops a machine learning model to predict the impact of missense variants in human filamin C, achieving high accuracy in distinguishing pathogenic from non-pathogenic variants.

bioRxiv · Aug 5, 2023 · PreprintBiophysics

Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle.

J. W. McNamara, B. L. Parker, H. K. Voges, N. R. R. Mehdiabadi, F. Bolk, D. D. Chung, N. Charitakis, J. Molendijk, S. Lal, M. Ramialison, K. Karavendzas, H. L. Pointer, P. Syrris, L. R. Lopes, E. M. Perry, , D. A. Elliott

This study identifies ALPK3's role in maintaining sarcomere integrity and proteostasis in striated muscle by localizing to the M-band and interacting with SQSTM1.

bioRxiv · Sep 1, 2022Cell Biology