Author

L. R. Martinez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. E. Munzen· 4 shared C. L. Charles-Nino· 2 shared H. H. Lee· 2 shared K. Alvina· 2 shared M. F. Hamed· 2 shared M. Hamed· 2 shared M. R. Dores· 2 shared M. Reguera Gomez· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersMicrobiology

M. E. Munzen

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Palmitoylethanolamide shows limited efficacy in controlling cerebral cryptococcosis in vivo

M. E. Munzen, M. Reguera Gomez, M. Hamed, V. Enriquez, C. L. Charles-Nino, M. R. Dores, K. Alvina, L. R. Martinez

This study evaluates PEA's efficacy in treating cerebral cryptococcosis, finding it ineffective alone but additive when combined with AmpB, though less effective than standard AmpB and 5-FC treatment.

bioRxiv · Apr 10, 2023 · PreprintMicrobiology

Clinical and pathological characterization of Central Nervous System cryptococcosis in an experimental mouse model of stereotaxic intracerebral infection

M. Hamed, V. Enriquez, M. E. Munzen, C. L. Charles-Nino, M. R. Mihu, H. Khoshbouei, K. Alvina, L. R. Martinez

This study uses a mouse model to investigate CNS cryptococcosis progression, finding region-specific histopathology and GXM-related immune responses.

PLOS Neglected Tropical Diseases · Jan 19, 2023Peer-reviewedMicrobiology

Glucuronoxylomannan intranasal challenge prior to Cryptococcus neoformans pulmonary infection enhances cerebral cryptococcosis in rodents

H. H. Lee, D. J. Carmichael, V. Ribeiro, D. N. Parisi, M. E. Munzen, M. F. Hamed, E. Kaur, A. Mishra, J. Patel, R. Rooklin, A. Sher, M. A. Carrillo-Sepulveda, E. A. Eugenin, M. R. Dores, L. R. Martinez

This study shows that intranasal GXM administration before C. neoformans infection increases fungal burden in lungs and enhances brain invasion by disrupting the blood-brain barrier.

bioRxiv · Oct 24, 2022 · PreprintMicrobiology

Phospholipase B is critical for Cryptococcus neoformans survival in the central nervous system

M. F. Hamed, G. Araujo, M. E. Munzen, M. Reguera Gomez, C. Epstein, H. H. Lee, s. frases, L. R. Martinez

This study shows that phospholipase B (PLB1) is essential for Cryptococcus neoformans survival in the central nervous system, as its deletion reduces fungal load and virulence in mice.

bioRxiv · Sep 18, 2022Microbiology