Engineered neuron-targeting, placental mesenchymal stromal cell-derived extracellular vesicles for in utero treatment of myelomeningocele
X. Zhang, H. Chen, K. Gao, S. He, Z. Ma, R. Liu, D. Hao, Y. Wang, P. Kumar, L. Ramasubramanian, C. D. Pivetti, Y. Li, F. Guo, F. Wang, R. Carney, , A. Wang
This paper engineers neuron-targeting extracellular vesicles for in utero treatment of myelomeningocele, showing improved neuroprotection and reduced apoptosis in a rodent model.
bioRxiv · Sep 22, 2021 · PreprintBioengineering