Efficient culture of SARS-CoV-2 in human hepatoma cells enhances viability of the virus in human lung cancer cell lines permitting the screening of antiviral compounds
S. Ramirez, C. Fernandez-Antunez, L. V. Pham, L. A. Ryberg, S. Feng, M. S. Pedersen, L. S. Mikkelsen, S. Belouzard, J. Dubuisson, J. M. Gottwein, U. Fahnoe, J. Bukh
This paper adapts SARS-CoV-2 to replicate more efficiently in human cells, enabling antiviral compound screening across multiple cell lines.
bioRxiv · Oct 4, 2020 · PreprintMicrobiology