Author

L. A. Ryberg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3

Frequent Co-Authors

C. Fernandez-Antunez· 2 shared J. Bukh· 2 shared J. M. Gottwein· 2 shared L. V. Pham· 2 shared S. Ramirez· 2 shared U. Fahnoe· 2 shared A. Binderup· 1 shared A. L. Nielsen· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMicrobiology

C. Fernandez-Antunez

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3 papers

Recent·Most cited

Fluorogenic Substrates and Cyclic Peptide Inhibitors of the Oligonucleotide Activated SIRT7

J. E. Bolding, A. L. Nielsen, I. Jensen, T. N. Hansen, L. A. Ryberg, S. T. Jameson, P. Harris, G. H. Peters, J. Denu, J. M. Rogers, C. A. Olsen

This study develops fluorogenic assays and cyclic peptide inhibitors to probe SIRT7 activity and selectivity, revealing its monomeric structure and substrate preferences.

bioRxiv · Jun 16, 2023 · PreprintBiochemistry

Nirmatrelvir Resistant SARS-CoV-2 Variants with High Fitness in Vitro

Y. Zhou, K. A. Gammeltoft, L. A. Ryberg, L. V. Pham, U. Fahnoe, A. Binderup, C. R. D. Hernandez, A. Offersgaard, C. Fernandez-Antunez, G. H. J. Peters, S. Ramirez, J. Bukh, J. M. Gottwein

This study identifies nirmatrelvir-resistant SARS-CoV-2 variants with high in vitro fitness and shows that remdesivir remains effective against them.

bioRxiv · Jun 6, 2022Microbiology

Efficient culture of SARS-CoV-2 in human hepatoma cells enhances viability of the virus in human lung cancer cell lines permitting the screening of antiviral compounds

S. Ramirez, C. Fernandez-Antunez, L. V. Pham, L. A. Ryberg, S. Feng, M. S. Pedersen, L. S. Mikkelsen, S. Belouzard, J. Dubuisson, J. M. Gottwein, U. Fahnoe, J. Bukh

This paper adapts SARS-CoV-2 to replicate more efficiently in human cells, enabling antiviral compound screening across multiple cell lines.

bioRxiv · Oct 4, 2020 · PreprintMicrobiology