Author

L. Soucek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

G. I. Evan· 1 shared L. Brown Swigart· 1 shared L. Pellegrinet· 1 shared M. J. Arends· 1 shared N. M. Sodir· 1 shared R. M. Kortlever· 1 shared S. Kupczak· 1 shared T. Campos· 1 shared

Activity by Year

2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

G. I. Evan

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1 paper

Recent·Most cited

Myc instructs and maintains pancreatic adenocarcinoma phenotype

N. M. Sodir, R. M. Kortlever, V. J. Barthet, L. Pellegrinet, T. Campos, S. Kupczak, L. Brown Swigart, L. Soucek, M. J. Arends, T. D. Littlewood, G. I. Evan

This study shows Myc activation in PanIN cells drives the transition to PDAC by instructing a fibroinflammatory stroma, and its deactivation reverses the phenotype, suggesting Myc as a reversible molecular switch for PDAC.

bioRxiv · Feb 21, 2019Cancer Biology