Author

L. Vahdat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. McGregor· 1 shared A.-A. Varlet· 1 shared D. Kim· 1 shared D. Mercatelli· 1 shared D. Ziegler· 1 shared E. Kasiou· 1 shared E. M. Poursani· 1 shared E. S. Bell· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. L. McGregor

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2 papers

Recent·Most cited

Copper chelation inhibits TGF-β pathways and suppresses epithelial-mesenchymal transition in cancer

E. M. Poursani, D. Mercatelli, P. Raninga, J. L. Bell, F. Saletta, F. V. Kohane, Y. Zheng, J. Rouaen, T. R. Jue, F. T. Michniewicz, E. Kasiou, M. Tsoli, G. Cirillo, S. Waters, T. Shai-Hee, , O. VITTORIO

This paper shows copper chelation inhibits TGF-β pathways and reduces EMT in cancer cells, potentially offering a new therapeutic strategy for targeting TGF-β in cancer.

bioRxiv · Oct 3, 2022 · PreprintCancer Biology

Low lamin A levels enhance confined cell migration and metastatic capacity in breast cancer

E. S. Bell, P. Shah, N. Zuela - Sopilniak, D. Kim, A.-A. Varlet, J. L. P. Morival, A. L. McGregor, P. Isermann, P. Davidson, J. J. Elacqua, J. Lakins, L. Vahdat, V. Weaver, M. B. Smolka, P. Span, J. Lammerding

This study shows that low lamin A levels in breast cancer cells increase nuclear deformability and metastatic capacity, with lower lamin A levels linked to poorer disease-free survival in human tumors.

Oncogene · Jul 27, 2022Peer-reviewedCancer Biology