Author

L. Wiggins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Assay:imaging· 2 Research Focus:spatial domain detection· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

W. J. Brackenbury· 2 shared A. D. James· 1 shared A. Gambus· 1 shared A. J. Kennerley· 1 shared A. L. B. Pyne· 1 shared D. Racko· 1 shared E. P. Holmes· 1 shared F. J. Gilbert· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

W. J. Brackenbury

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Author profile →

3 papers

Recent·Most cited

Under or Over? Tracing Complex DNA Structures with High-Resolution Atomic Force Microscopy

E. P. Holmes, M. C. Gamill, J. I. Provan, L. Wiggins, R. Ruskova, S. Whittle, T. E. Catley, K. H. S. Main, N. Shephard, H. E. Bryant, N. S. Gilhooly, A. Gambus, D. Racko, S. D. Colloms, A. L. B. Pyne

This paper introduces a high-throughput AFM-based pipeline using deep learning to trace DNA topology, revealing new insights into DNA structures and their interactions.

bioRxiv · Jun 28, 2024Biophysics

Exploring the impact of variability in cell segmentation and tracking approaches

L. Wiggins, P. J. O'Toole, W. J. Brackenbury, J. Wilson

The paper quantifies variability in manual and automated cell segmentation and tracking methods, showing their impact on phenotypic metrics and reproducibility.

bioRxiv · Nov 24, 2023Cell Biology

Sodium accumulation in breast cancer predicts malignancy and treatment response

A. D. James, T. K. Leslie, J. D. Kaggie, L. Wiggins, L. Patten, J. M. O'Duinn, S. Langer, M.-C. Labarthe, F. Riemer, G. Baxter, M. A. McLean, F. J. Gilbert, A. J. Kennerley, W. J. Brackenbury

This study uses 23Na MRI to show elevated sodium levels in breast tumors, which correlate with malignancy and treatment response, offering a non-invasive biomarker.

bioRxiv · Apr 14, 2021Cancer Biology