Author

L.-G. Bekker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Assay:metagenomics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Crowther· 2 shared G. Gray· 2 shared P. Kgagudi· 2 shared A. Alisoltani· 1 shared A. Godzik· 1 shared A. Grier· 1 shared A. Iranzadeh· 1 shared A. Koen· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

C. Crowther

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages

J. N. Bhiman, S. I. Richardson, B. E. Lambson, P. Kgagudi, N. Mzindle, H. Kaldine, C. Crowther, G. Gray, L.-G. Bekker, A. Koen, L. Fairlie, L. Fouche, Q. Bhorat, K. Dheda, M. Tameris, , P. L. Moore

This study evaluates the neutralizing antibody response to NVX-CoV2373 against Omicron sub-lineages after two or three doses, showing improved neutralization with a third dose.

bioRxiv · Jul 14, 2022 · PreprintImmunology

Transkingdom Analysis of the Female Reproductive Tract Reveals Bacteriophages Form Communities

F. S. Madere, M. Sohn, A. Winbush, B. Barr, A. Grier, J. Java, T. Meiring, A.-L. Williamson, L.-G. Bekker, D. H. Adler, C. L. Monaco

The paper analyzes the FRT virome and bacteriome in BV-positive and BV-negative women, finding distinct bacteriophage signatures associated with bacterial vaginosis.

bioRxiv · Oct 12, 2021Microbiology

Neutralizing antibodies elicited by the Ad26.COV2.S COVID-19 vaccine show reduced activity against 501Y.V2 (B.1.351), despite protection against severe disease by this variant.

P. Moore, T. Moyo, T. Hermanus, P. Kgagudi, F. Ayres, Z. Makhado, J. Sadoff, M. Le Gars, G. van Roey, C. Crowther, N. Garrett, L.-G. Bekker, L. Morris, H. Schuitemaker, G. Gray

The study assesses neutralizing antibody activity against 501Y.V2 variant post-Ad26.COV2.S vaccination, finding reduced neutralization but potential protection via other immune mechanisms.

bioRxiv · Jun 9, 2021 · PreprintImmunology

Microbial function and genital inflammation in young South African women at high risk of HIV infection

A. Alisoltani, M. T. Manhanzva, M. G. Potgieter, C. Balle, L. Bell, E. Ross, A. Iranzadeh, M. du Plessis, N. Radzey, Z. McDonald, B. Calder, I. Allali, N. Mulder, S. Dabee, S. Barnabas, , L. Masson

This study uses metaproteomics to link microbial function and inflammation in the female genital tract of South African women at high HIV risk, finding that reduced cell wall organization and peptidoglycan biosynthesis are associated with high inflammation.

Microbiome · Nov 21, 2020Peer-reviewedMicrobiology