Author

H. Kaldine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:proteomics· 1

Frequent Co-Authors

B. E. Lambson· 2 shared P. Kgagudi· 2 shared A. A. Murji· 1 shared A. Bodenstein· 1 shared A. Koen· 1 shared C. Bennett· 1 shared C. Crowther· 1 shared C. Grobbelaar· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

B. E. Lambson

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3 papers

Recent·Most cited

Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages

J. N. Bhiman, S. I. Richardson, B. E. Lambson, P. Kgagudi, N. Mzindle, H. Kaldine, C. Crowther, G. Gray, L.-G. Bekker, A. Koen, L. Fairlie, L. Fouche, Q. Bhorat, K. Dheda, M. Tameris, , P. L. Moore

This study evaluates the neutralizing antibody response to NVX-CoV2373 against Omicron sub-lineages after two or three doses, showing improved neutralization with a third dose.

bioRxiv · Jul 14, 2022 · PreprintImmunology

Fc effector activity and neutralization against SARS-CoV-2 BA.4 is compromised in convalescent sera, regardless of the infecting variant

S. Richardson, P. Kgagudi, N. P. Manamela, H. Kaldine, E. Venter, T. Pillay, B. E. Lambson, M. van der Mescht, T. Hermanus, Z. de Beer, T. de Villier, A. Bodenstein, G. van den Berg, M. du Pisanie, W. Burgers, , P. Moore

This study shows that convalescent sera and post-vaccination breakthrough infections have reduced neutralization and ADCC activity against SARS-CoV-2 BA.4, despite prior infection with different variants.

bioRxiv · Jul 14, 2022 · PreprintImmunology

Sequence and functional characterization of a public HIV-specific antibody clonotype

A. A. Murji, N. Raju, J. S. Qin, H. Kaldine, K. Janowska, E. F. Fechter, R. Mapengo, C. Scheepers, I. Setliff, P. Acharya, L. Morris, I. S. Georgiev

The paper characterizes a public HIV-specific antibody clonotype from three individuals, showing that antigen specificity is modulated by VH germline genes and that non-native heavy-light chain pairings maintain consistent antigen recognition.

bioRxiv · May 14, 2021Immunology