Author

L.-Y. Wu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. M. Martins· 1 shared A. O. Harrison· 1 shared B. D. Ferrell· 1 shared B. He· 1 shared B. Zhang· 1 shared C. Xiao· 1 shared C. Zhang· 1 shared C.-K. Chang· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperEcology

A. M. Martins

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Biologically informed machine learning modeling of immune cells to reveal physiological and pathological aging process

C. Zhang, T. Ren, X. Zhao, Y. Su, Q. Wang, T. Zhang, B. He, L.-Y. Wu, L. Sun, B. Zhang, Z. Xia

The paper constructs a transcriptomic atlas of immune cells across human lifespan and develops a biological age prediction model using scRNA-seq and bulk RNA-seq data.

bioRxiv · Apr 1, 2024Immunology

B12-dependent virioplankton demonstrate interseasonal dynamics and associate with a diversity of pelagic bacterioplankton

L.-Y. Wu, G. J. Piedade, R. M. Moore, A. O. Harrison, A. M. Martins, K. D. Bidle, S. W. Polson, E. Sakowski, J. I. Nissimov, J. T. Dums, B. D. Ferrell, K. E. Wommack

This study examines B12-dependent viral populations in pelagic ecosystems, showing seasonal dynamics and associations with diverse bacterioplankton.

bioRxiv · Mar 13, 2023Ecology

Somatic mutations of activated signaling genes, transcription factors, or tumor suppressors are a precondition for leukemic transformation from myelodysplastic syndromes: a sequencing analysis of 64 paired samples

X. Li, C.-K. Chang, F. Xu, L.-Y. Wu, J. Guo, L.-X. Song, Y. Tao, Q. He, Z. Zhang, D. Wu, L.-Y. Zhou, C. Xiao, J.-Y. Su

bioRxiv · May 28, 2021 · PreprintCancer Biology

BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia

Y.-L. He, S.-H. Gong, X. Cheng, M. Zhao, T. Zhao, Y. Zhao, M. Fan, L.-L. Zhu, L.-Y. Wu

This study shows that JNK1/2 phosphorylates BNIP3 under hypoxia, enhancing its stability and promoting mitophagy by increasing its binding to LC3.

bioRxiv · Aug 27, 2020Cell Biology