RNF13 mediates pH- and Ca2+-dependent regulation of lysosomal positioning
Lan Thi Trinh, Anh Vu, Seung Ho Shin, Chanhaeng Lee, Sanghee Park, Eun-Bee Cho, Yunseok Heo, Hyun Jin Kim, Sungjoo Kim, Jong‐Bok Yoon
This study identifies RNF13 as a regulator of lysosomal positioning, showing its activity is controlled by pH and Ca2+ levels through interactions with ALG-2 and ARL8B.
Cell Reports · Jul 24, 2025Peer-reviewedCell Biology