Author

Lan-Zhen Wang

Newcastle University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Anita Wittner· 1 shared Claire JenningsiD· 1 shared Eleanor K. Wright· 1 shared Gina M. DoodyiD· 1 shared Ian HicksoniD· 1 shared Julie A. TuckeriD· 1 shared Martin E. M. NobleiD· 1 shared Mathew P. MartiniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Anita Wittner

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1 paper

Recent·Most cited

Structural, biophysical and biological analysis and characterisation of IRF4 DNA-binding domain mutations associated with multiple myeloma

Natalie J. Tatum, Rebecca Scott, Gina M. Doody, Ian Hickson, Claire Jennings, Mathew P. Martin, Reuben M. Tooze, Julie A. Tucker, Anita Wittner, Lan-Zhen Wang, Eleanor K. Wright, Stephen R. Wedge, Martin E. M. Noble

The paper analyzes IRF4 DNA-binding domain mutations in multiple myeloma, finding they affect DNA-binding kinetics and thermal stability but not affinity, and may confer improved prognosis.

bioRxiv · Mar 12, 2025 · PreprintBiophysics