Author

Lara F. Tshering

Pfizer (United States)

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Molecular Biology· 1

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Approach:experimental assay· 1 Organism:human· 1

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Alicia SolórzanoiD· 1 shared Azadeh PaksaiD· 1 shared Chong WangiD· 1 shared Javier F. Chaparro‐RiggersiD· 1 shared Laura LiniD· 1 shared Qing XiangiD· 1 shared Sharmistha Kundu· 1 shared

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2025-2025 · peak 1/yr

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Alicia SolórzanoORCID

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1 paper

Recent·Most cited

Self-amplifying mRNA expression is governed by mitochondrial machinery and ACSL4

Lara F. Tshering, Chong Wang, Qing Xiang, Sharmistha Kundu, Alicia Solórzano, Javier F. Chaparro‐Riggers, Laura Lin, Azadeh Paksa

The paper identifies mitochondrial function and ACSL4 as key regulators of self-amplifying mRNA (saRNA) expression, showing that modulating ACSL4 improves saRNA expression across cell types.

bioRxiv · Jun 13, 2025 · PreprintMolecular Biology