Author

Lars Hellweg

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Jasper B. Lee· 1 shared Kai W. WucherpfennigiD· 1 shared Maria Caterina RotirotiiD· 1 shared Robbie G. MajzneriD· 1 shared Susanna K. ElledgeiD· 1 shared Xin X. ZhouiD· 1 shared Zhixing Ma· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Jasper B. Lee

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1 paper

Recent·Most cited

Synthetic signaling platform uncovers and rewires cellular responses to PD-1 perturbation

Zhixing Ma, Lars Hellweg, Susanna K. Elledge, Jasper B. Lee, Maria Caterina Rotiroti, Kai W. Wucherpfennig, Robbie G. Majzner, Xin X. Zhou

The paper introduces Sphyder, a tool to detect and rewire phosphorylation motifs, revealing PD-1 signaling mechanisms and enabling synthetic receptor design for immunotherapy.

bioRxiv · Oct 1, 2025 · PreprintImmunology