Dynamic anatomy of the replisome under stress
Larua Schulte, Maruthi Kumar Pabba, Maliwan Kamkaew, Paulina Prorok, María Arroyo, M. Cristina Cardoso
This study tracks replisome dynamics under replication stress using live-cell imaging, showing polymerase accumulation, clamp loading near stalled forks, and preferential restart at new origins after stress removal.
bioRxiv · Jun 4, 2026 · PreprintCell Biology