BCG-induced reprogramming of monocyte/macrophage populations enhances lung antitumor immunity in mice
Eduardo Moreo, Miguel Araujo‐Voces, Luna Minute, Laura Bravo-Robles, Ana Jiménez, Santiago Uranga, Ana Belén Gómez, Carlos Martı́n, Carlos del Fresno, Nacho Aguiló
This study shows that IV BCG reprograms monocyte/macrophage populations in mice, shifting them to pro-inflammatory phenotypes that enhance antitumor immunity by boosting NK and T cell responses.
bioRxiv · Jul 25, 2025 · PreprintImmunology