Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration
Nader Morshed, William T. Ralvenius, Alexi Nott, Lauren Ashley Watson, Felicia H. Rodriguez, Leyla Anne Akay, Brian A. Joughin, Ping‐Chieh Pao, Jay Penney, Lauren M. LaRocque, Diego Mastroeni, Li‐Huei Tsai, Forest M. White
The paper uses phosphoproteomics to identify Siglec-F and Siglec-8 as upregulated in microglia during neurodegeneration, driving inflammatory responses in mouse and human models.
Molecular Systems Biology · Dec 1, 2020Peer-reviewedNeuroscience