Author

Gunnar Mellgren

Haukeland University HospitalORCID 0000-0001-6282-4986Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

Jan-Inge BjuneiD· 2 shared Kamal MustafaiD· 2 shared Pouda PanahandehiD· 2 shared Shuntaro YamadaiD· 2 shared Simon EN DankeliD· 2 shared Elisabeth WikiD· 1 shared Emmet McCormackiD· 1 shared Karianne FjeldiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Jan-Inge BjuneORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 21, 2026

ERα-regulated IRX3 controls the growth of ER-positive breast tumors

Pouda Panahandeh, Jan-Inge Bjune, Regine Åsen Jersin…·Gunnar Mellgren

This study identifies IRX3 as an ERα-regulated gene that promotes ER+ breast tumor growth and metastasis by enhancing vascularization, with low IRX3 expression linked to poorer patient survival.

DOI 10.64898/2026.05.20.725898

humanbulk RNA-seq

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Molecular BiologyNature CommunicationsPeer-reviewedAug 6, 2025

Mechanisms of the FTO locus association with obesity: Irx3 controls a sumoylation-dependent switch between adipogenesis and osteogenesis

Jan-Inge Bjune, Samantha Laber, Laurence Lawrence‐Archer…·Simon N. Dankel

This study identifies IRX3 as a regulator of sumoylation that controls adipogenesis and osteogenesis through epigenetic mechanisms, linking the FTO locus to obesity.

7 citations

mouseATAC-seq

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