Author

Lei Hou

Boston University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Developmental Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Di CheniD· 1 shared Dongzhi WangiD· 1 shared Heng ZengiD· 1 shared Jian-Xiong Chen· 1 shared Jiayao CheniD· 1 shared Jin JiangiD· 1 shared John S. ClemmeriD· 1 shared Lihong PaniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperDevelopmental Biology

Di ChenORCID

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Author profile →

2 papers

Recent·Most cited

IL27 exerts a powerful effect on systolic overload-induced cardiac inflammation, fibrosis, and heart failure development

Ziru Niu, Umesh Bhattarai, Dongzhi Wang, Xiaochen He, Lihong Pan, Heng Zeng, Jian-Xiong Chen, John S. Clemmer, Lei Hou, Yingjie Chen

This study shows IL-27 promotes cardiac inflammation, fibrosis, and heart failure in mice by modulating immune and non-immune cells, suggesting it as a therapeutic target.

Redox Biology · Oct 1, 2026Peer-reviewedPhysiology

Integrated analysis and systematic characterization of the regulatory network for human germline development

Yashi Gu, Jiayao Chen, Ziqi Wang, Qizhe Shao, Zhekai Li, Yaxuan Ye, Xia Xiao, Yitian Xiao, Wenyang Liu, Sisi Xie, Lingling Tong, Jin Jiang, Xiaoying Xiao, Ya Yu, Min Jin, , Di Chen

The paper integrates multi-omics data to characterize the regulatory network governing human germline development and identifies key factors and interactions involved.

Journal of genetics and genomics/Journal of Genetics and Genomics · Nov 19, 2024Peer-reviewedDevelopmental Biology