Umesh Bhattarai

This study shows IL-27 promotes cardiac inflammation, fibrosis, and heart failure in mice by modulating immune and non-immune cells, suggesting it as a therapeutic target.

This study shows that genetic inhibition of IL-12β reduces cardiac inflammation and heart failure in mice subjected to transverse aortic constriction.

This study shows Nck1, but not Nck2, mediates shear stress-induced endothelial permeability through distinct signaling mechanisms.