Author

Heng Zeng

University of Mississippi Medical CenterORCID 0000-0001-8559-2807Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Dongzhi WangiD· 2 shared John S. ClemmeriD· 2 shared Lihong PaniD· 2 shared Umesh BhattaraiiD· 2 shared Xiaochen HeiD· 2 shared Yingjie CheniD· 2 shared Ziru Niu· 2 shared Hao WangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersPhysiology

Dongzhi WangORCID

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2 papers

Recent·Most cited

PhysiologyRedox BiologyPeer-reviewedOct 1, 2026

IL27 exerts a powerful effect on systolic overload-induced cardiac inflammation, fibrosis, and heart failure development

Ziru Niu, Umesh Bhattarai, Dongzhi Wang…·Yingjie Chen

This study shows IL-27 promotes cardiac inflammation, fibrosis, and heart failure in mice by modulating immune and non-immune cells, suggesting it as a therapeutic target.

DOI 10.1016/j.redox.2026.104459

mouseexperimental assay

𝕏 PostBluesky

PhysiologybioRxivPreprintSep 5, 2025

Genetic inhibition of IL-12β suppresses systolic overload-induced cardiac inflammation and heart failure development

Umesh Bhattarai, Xiaochen He, Ziru Niu…·Yingjie Chen

This study shows that genetic inhibition of IL-12β reduces cardiac inflammation and heart failure in mice subjected to transverse aortic constriction.

DOI 10.1101/2025.09.05.674485

mousebulk RNA-seq

𝕏 PostBluesky