Author

Lei Ni

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:cell signaling & trafficking· 2 Approach:microscopy & imaging analysis· 2 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Approach:optimal transport· 1

Frequent Co-Authors

Fan JiniD· 3 shared Aiguo Xia· 2 shared Lu PuiD· 2 shared Shuai YangiD· 2 shared Yajia HuangiD· 2 shared Guang Yang· 1 shared Haiyi LiangiD· 1 shared Hui Wen· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersMicrobiology

Fan JinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Pressorum Sensing: Growth-induced Compression Activates cAMP Signaling in Pseudomonas aeruginosa

Lei Ni, Yajia Huang, Yaoxin Huang, Yue Yu, Jiarui Xiong, Hui Wen, Wenwen Xiao, Haiyi Liang, Fan Jin

This paper introduces pressorum sensing in Pseudomonas aeruginosa, showing mechanical compression triggers cAMP signaling via the Pil-Chp system, leading to increased virulence.

bioRxiv · Jul 8, 2024 · PreprintMicrobiology

Engineering Gac/Rsm signaling cascade for optogenetic induction of pathogenicity switch in Pseudomonas aeruginosa

Xinyi Cheng, Lu Pu, Shengwei Fu, Aiguo Xia, Shuqiang Huang, Lei Ni, Xiaochen Xing, Shuai Yang, Fan Jin

This paper introduces an optogenetic system to control bacterial pathogenicity in specific host tissues by engineering the Gac/Rsm signaling cascade in Pseudomonas aeruginosa.

ACS Synthetic Biology · Jun 2, 2021Peer-reviewedSynthetic Biology

Optogenetics reprogramming of planktonic cells for biofilm formation

Aiguo Xia, Shuai Yang, Yajia Huang, Zhenyu Jin, Lei Ni, Lu Pu, Guang Yang, Fan Jin

This study develops ATI, a method to control biofilm formation in Pseudomonas aeruginosa by manipulating single-cell behaviors through optogenetics and tracking.

bioRxiv · Dec 4, 2017 · PreprintMicrobiology