Author

Lei Yuan

Shaanxi Normal University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Organism:Drosophila· 1

Frequent Co-Authors

Fuqiao LiuiD· 3 shared Hui WangiD· 3 shared Hui Xiao· 3 shared Qian ZhengiD· 3 shared Peiyao LiiD· 2 shared Yunmin Xie· 2 shared Aiying Ma· 1 shared Aowei Wang· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCell Biology

Fuqiao LiuORCID

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3 papers

Recent·Most cited

The evolutionarily conserved APP-Spastin cooperation regulates endolysosomal homeostasis and apoptotic cell degradation

Qian Zheng, Fuqiao Liu, Lei Yuan, Zhulin Liu, Haibing Lv, Tong Xiao, Zheng Cui, Qiyuan Zhong, Hui Wang, Qiuyuan Yin, Hui Xiao

This study identifies a conserved non-amyloidogenic role for APP in regulating endolysosomal homeostasis and apoptotic cell degradation through its interaction with Spastin.

bioRxiv · Jul 15, 2026 · PreprintCell Biology

The engulfment receptor CED-1/MEGF10 activates the GPCR LAT-1/ADGRL3 for apoptotic cell degradation

Fuqiao Liu, Lei Yuan, Qian Zheng, Yang Kang, Aowei Wang, Kuo Li, Yunmin Xie, Lu Chen, Peiyao Li, Hui Wang, Zhi Li, Hui Xiao

This study identifies a conserved signaling pathway involving CED-1/MEGF10 and LAT-1/ADGRL3 that regulates apoptotic cell clearance through a transcriptional cascade.

bioRxiv · Jun 10, 2026 · PreprintCell Biology

GEI-17-Mediated SUMOylation of GDI-1 Regulates Apoptotic Cell Clearance

Lei Yuan, Peiyao Li, Aiying Ma, Chao Li, fuqiao liu, Yunmin Xie, Qian Zheng, Hui Wang, Hui Xiao

This study identifies GEI-17-mediated SUMOylation of GDI-1 as a mechanism regulating phagosomal degradation and apoptotic cell clearance in C. elegans and mammals.

bioRxiv · Jan 22, 2025 · PreprintCell Biology