Hui Wang

This study identifies a conserved non-amyloidogenic role for APP in regulating endolysosomal homeostasis and apoptotic cell degradation through its interaction with Spastin.

This study identifies a conserved signaling pathway involving CED-1/MEGF10 and LAT-1/ADGRL3 that regulates apoptotic cell clearance through a transcriptional cascade.

This study shows hepatocyte PLD1 knockout changes gut microbiota and bile acid profiles in MASLD mice, suggesting PLD1 deficiency modulates disease progression via microbiota-bile acid homeostasis.

This study reports the discovery of using antisense oligonucleotides (ASOs) to rescue the biallelic SEL1L C141Y variant, offering a potential therapeutic strategy.

This study identifies GEI-17-mediated SUMOylation of GDI-1 as a mechanism regulating phagosomal degradation and apoptotic cell clearance in C. elegans and mammals.

This study examines the effects of terahertz radiation on rat hippocampal neurons, finding that different power densities and exposure times influence cell activity and apoptosis but not morphology or amino acid levels.