Author

Lena Ludwig

RWTH Aachen University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Aaron BabendreyeriD· 1 shared Andreas LudwigiD· 1 shared Caroline C. F. GrannemanniD· 1 shared Charlotte Flasshove· 1 shared Colin AdrainiD· 1 shared Diandra T. KelleriD· 1 shared Friederike Sonnabend· 1 shared Jens Malte BaroniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Aaron BabendreyerORCID

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1 paper

Recent·Most cited

Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity.

Katharina Bläsius, Lena Ludwig, Sarah Knapp, Charlotte Flasshove, Friederike Sonnabend, Diandra T. Keller, Nikola Tacken, Xintong Gao, Selcan Kahveci-Türköz, Caroline C. F. Grannemann, Aaron Babendreyer, Colin Adrain, Sebastian Huth, Jens Malte Baron, Andreas Ludwig, Stefan Düsterhöft

This study identifies a phosphorylation-independent 14-3-3 interaction site in iRhom2's N-terminus that regulates ADAM17 activity and shows how mutations in this region cause different pathological outcomes.

Cellular and Molecular Life Sciences · Feb 26, 2024Peer-reviewedMolecular Biology