Author

Andreas Ludwig

RWTH Aachen UniversityORCID 0000-0001-8536-4986Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:protein design· 2 Assay:protein structure· 2 Research Focus:differential expression· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Stefan DüsterhöftiD· 3 shared Aaron BabendreyeriD· 2 shared Christine LuxiD· 2 shared Katharina Schun· 2 shared Selcan Kahveci-TürköziD· 2 shared C Martin· 1 shared Caroline C. F. GrannemanniD· 1 shared Charlotte Flasshove· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Stefan DüsterhöftORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologyScientific ReportsPeer-reviewedJul 8, 2026

Naturally occurring ACE2 stalk variants are differentially released from the cell.

Florian Wiersch, Christine Lux, Julia Vanderliek‐Kox…·Stefan Düsterhöft

The paper identifies naturally occurring ACE2 stalk variants that differentially affect soluble ACE2 release and surface expression of B0AT1.

1 citationtop 5%

humanprotein structure

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivPreprintJun 9, 2026

The pseudoproteinase iRhom2 critically promotes acute lung inflammation

Christine Lux, Selcan Kahveci-Türköz, Katharina Schun…·Andreas Ludwig

This study shows that iRhom2 deficiency reduces acute lung inflammation in mice by impairing ADAM17-mediated shedding of inflammatory mediators and neutrophil recruitment.

DOI 10.64898/2026.06.05.730404

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologyCellular and Molecular Life SciencesPeer-reviewedFeb 26, 2024

Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity.

Katharina Bläsius, Lena Ludwig, Sarah Knapp…·Stefan Düsterhöft

This study identifies a phosphorylation-independent 14-3-3 interaction site in iRhom2's N-terminus that regulates ADAM17 activity and shows how mutations in this region cause different pathological outcomes.

12 citations

𝕏 PostBluesky