Author

Lia Lee

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:optimal transport· 1 Assay:scRNA-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Aryeh SolomoniD· 1 shared Aviv RegeviD· 1 shared Brian ClearyiD· 1 shared Eric S. LanderiD· 1 shared Geoffrey R. SchiebingeriD· 1 shared Jenny CheniD· 1 shared Jian ShuiD· 1 shared Justin BrumbaughiD· 1 shared

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2017-2017 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Aryeh SolomonORCID

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1 paper

Recent·Most cited

Reconstruction of developmental landscapes by optimal-transport analysis of single-cell gene expression sheds light on cellular reprogramming.

Geoffrey R. Schiebinger, Jian Shu, Marcin Tabaka, Brian Cleary, Vidya Subramanian, Aryeh Solomon, Siyan Liu, Stacie L. Lin, Peter Berube, Lia Lee, Jenny Chen, Justin Brumbaugh, Philippe Rigollet, Konrad Hochedlinger, Rudolf Jaenisch, , Eric S. Lander

Optimal transport converts a 65,781-cell reprogramming time course into probabilistic fates and trajectories, exposing alternative cell fates and a gene, Obox6, that improves reprogramming efficiency.

bioRxiv · Sep 27, 2017 · PreprintBioinformatics